Poster List

GENETICS I HEMATOPATHOLOGY I INFECTIOUS DISEASES I INFORMATICS I OTHER (EDUCATION, ETC.) I SOLID TUMORS I TECHNICAL TOPICS 

Odd numbered posters will be attended by their authors on Tuesday, 4 April, 10:00 – 11:00

Even numbered posters will be attended by their authors on Wednesday 5 April, 10:00 – 11:00

GENETICS 

G01. Complete Sequencing of TTR Gene in Brazilian Amyloidosis Patients
N. Muto


G02. Cancer Risk Assessment in Over 50 Thousand Individuals Carrying HFE Gene Variants for Type 1 Hereditary Hemochromatosis 
N.S. Kip


G03. Exome Sequencing of Breast Cancer Familial Pedigree and Functional Cellular Characterization Identifies Novel DNA Double-strand Break Repair Deficient Mutation 
H. A. Costa


G04.  Clinical Exome Re-analysis: Keeping up with Gene Discovery
J.R. Murrell

G05. Establishment of a Rapid Genotyping System to Detect Obesity-associated Loci for Clinical Usage 
M.C. Wang


G06.  ID4 Allelic Variant is Associated with Endometriosis and May Affect Mesothelial Epithelial to Mesenchymal Transition
D. Dolderer

 

G07. Genetic Screening for Chromosomal Abnormalities and Y Chromosome Microdeletions in 992 Korean Infertile Men 
S.H. Han

 

G08. New Syndrome: First Patient with Heterozygous Deleterious PIG-Q Mutations Causing a GPI-anchor Biosynthesis Deficiency 
L. Starr


G09. The Role of the Chemokine RANTES (Regulated on Activation, Normal T-cell Expressed and Secreted) as a New Diagnostic Tool in Monitoring Cardiac Adiposity 
C.R. Massimiliano

 

G10. Implementation of a New Automated Sample Quality Control Tool in a Whole Exome Sequencing Workflow

E. Viering

 

G11.  Genomic Dosage Anomalies in Circulating Tumor Cells from Early Stage Breast Cancer Serve a Surrogates for Anomalies in Primary Tumors
J.N. Sanmann

 

G12.  Comparison of Buccal Specimens Collected with FLOQSwabs™ to Saliva and Blood for Genetic Investigations
S. Castriciano

 

G13. Development of Robust PCR Assays and a Simple Analysis Solution for CYP2D6 Copy Number Assessment by High-resolution Melting Analysis on Three Commercial Instruments 
L. Jiang

G14LB. Evaluation of a Home-brew NGS Assay for the Genetic Diagnosis of MODY Subtypes 1-3 
K.S. Poon

 

G15LB. Patterns of PML/RARA Gene Rearrangements by Interphase Fluorescence In Situ Hybridization in Acute Promyelocytic Leukemia 
M. Lee

 

G16LB. Analysis of Cell-free Plasma DNA for the Discrimination of Patients with Alcohol-induced Liver Cirrhosis from Liver Cancer Patients with a New Methylation Marker Panel 
A. Zipprich


HEMATOPATHOLOGY 

H01. Detection and Characterization of Genetic Aberration in Multiple Myeloma by Conventional and Molecular Cytogenetic Analyses 
J.Y. Han


H02. Small Customizable Next-Generation Sequencing Based Target Capture Panels in a Clinical Environment can Detect Variant Mutations at Frequencies as Low as 0.5% 
L. Chamberlain


H03. Analysis and Characterization of Hematologic Cancers Using a Comprehensive NGS Panel Comprised of DNA and RNA Baits Targeting 704 Genes
A. Carson

H04. Assessment of Minimal Residual Disease by NGS in Acute Myeloid Leukemia Patients by Monitoring FLT3 and NPM1 Mutations
Z. Xie
 

H05. Detection of Gene Amplification by Molecular Karyotyping in Acute Myeloid Leukemia with Marker Chromosomes 
E.J. Seo


H06. Routine Somatic Hypermutation Assessment in CLL/SLL by Next Generation Sequencing Captures Multidimensional Clinically Relevant Data and Demonstrates Higher Sensitivity than Traditional Methods 
K. Petrova-Drus

 

H07. ABC Subfamily C Member 10 (ABCC10) is a Promising Novel Target in Hodgkin's Lymphoma 
G.M. Abdel Salam 


H08. FISH Negative, RT-PCR Positive PML-RARA a Rare, Infrequent Phenomena in Acute Promyelocytic Leukemia: A Series of 5 Cases 
S.S. Vinarkar


H09.  Detecting Suspected B-cell Clonality using an NGS LymphoTrack IGH Assay
Y. Huang  


H10. MYD88, A20 and CARD11 in HIV Associated B-cell Lymphomas 
T. Shet


H11. Oligo-based Probes for the Rapid Detection of Lymphoma-associated Chromosomal Abnormalities in FFPE Samples 
J.N. Horne

 

H12. Molecular Abnormalities and their Correlation with the Prognosis of Younger Indian Patients with de novo Myelodysplastic Syndromes: AIIMS Study 
R. Chaubey

H13. Frequency of MYD88 and CXCR4 Mutation Profiling in Lymphoplasmcytic Lymphoma/Waldenstrom’s Macroglobulinaemia: Implications for the Molecular Laboratory
N. Arora

 

H14LB. Prevalence of Alpha Thalassemia Mutations among Filipinos in a Tertiary Care Setting
J. Malana

 

H15LB. Comprehensive Characterization of Targeted Sequencing Platforms to Elucidate AML-specific Mutational Landscapes
C. Fritz

 

H16LB. Assessment of WT1 Expression as a Marker of Treatment Outcome in Karyotype Normal Acute Myeloid Leukemia Patients in Pakistan
M.S. Shaikh

INFECTIOUS DISEASES
 

ID01. Developing Amplification Control and Extraction Control for Vaginal Health Research Workflow 
K. Li

 

ID02. Identification of a Multi-omic Signature Associated with Onset of GI Symptoms and Self-injurious Behavior in a Child with Autism Spectrum Disorder
R.A. Luna

 

ID03.  Rapid Detection and Identification of Uveitis Pathogens by Qualitative Multiplex Real Time PCR Followed by High Resolution Melting
P. Bispo

 

ID04.  Simultaneous Detection and Typing of Alpha, Beta and Gamma HPV Using Target Enrichment and Whole Genome Sequencing
T. Li

 

ID05. COPAN eNATTM Stabilizes Fecal Bacterial gDNA in Warm Climates and is Compatible with Microbiome Profiling Using the GA-map™ Dysbiosis Test

S. Castriciano

 

ID06.  MSwab™ Allows Viral Detection with Direct-Rapid Nucleic Acids Amplification and Culture Assays
S. Castriciano

 

ID07.  Characterization of Clinical Specimens Using GenMark’s ePlex® Blood Culture Identification (BCID) Panels
A. Thornberg

 

ID08. Clinical Evaluation of a Novel NGS-Based HIV-1 Drug Resistance Monitoring Test 
E. Rakhmanaliev


ID09. Comparison of Accupower TB&MDR Kit with Hain Genotype MTBDRPlus Kit for Detection of Mycobacterium Tuberculosis Drug Susceptibility in Pulmonary Samples 
M. Agrawal


ID10. Clinical Performance Evaluation of Lyophilized VIASURE Real Time PCR Detection Kits for Pathogen Detection by Participation in External Quality Assessment (EQA) Programs
C. Genzor


ID11. Comparison of Standard Reduced Transport Fluid (RTF) Buffer to the new eNAT Buffer Shows Vaginal Microbiome Stability for up to One Month in eNAT Buffer as Determined by the ISpro Microbiome Profiling 
S. Morre

 

ID12LB. Diagnostic Utility of Real-Time PCR for Mycobacterium Tuberculosis Complex Infection in Routine Clinical Practice
S. Shin

 

ID13LB. Usefulness of Molecular Test to Diagnose EBV Infection in Immunocompetent Patients
H.S. Kim


INFORMATICS 

I01. WITHDRAWN


I02. A Bayesian Network Algorithm for the Identification of Cancer Somatic Mutations in the Lack of Normal Tissue from Targeted High-throughput Sequencing Data
F. M. De La Vega

 

I03. Systematic Evaluation of Genetic Alterations for Cancer Precision Medicine Reports 
P. Kumar

 

I04LB.  Structural Variant Simulator improves Variant Calling Accuracy in NGS
A. Leon



OTHER (EDUCATION, ETC.) 


OTH01.  Application of the GeneReader NGS System in Analyzing a Diverse Set of Cancer Clinical Samples
L.  Oberauner-Wappis  


 

SOLID TUMORS 

ST01. HPV Detection and Genotyping in Formalin-fixed Paraffin Embedded Anal Lesions 
S.S. Koide


ST02. Automated Circulating Cell-free Tumor DNA (cfDNA) Extraction and Preparation for qPCR and NGS 
T. Ivanova

 

ST03. Targeted Bisulfite NGS of a DNA-methylation Multimarker Panel for Cancers of the Urinary Tract in Liquid Biopsies 
S. Karst


ST04.  Multiplex Detection of Oncogenic Fusion Transcripts and MET Exon Skipping by Molecular Counting in Lung Cancer
L. Moens


ST05. Head-to-head Comparison of Two Commercially Available Next-generation Sequencing Technologies that Detect Gene Fusions in Non-small Cell Lung Cancer 
R. Blidner


ST06.  Robust Mutation Profiles in Cancer Biopsies and Resections
K. Greene
 

ST07. Plasma Mutation Profile Reflects Active Cancer Status 
N.D. Montgomery 


ST08. Cancer of Unknown Primary Site: The Critical Role of the Genomics Profile and Public cBioPortal 
O. Rouhi


ST09. Circulating Tumor Cells Detection Using hTERT and MAGE A1-6 PCR and Conditionally Reprogrammed Cell Culture 
C.H. Jeon


ST10. High Expression of Aldolase B Confers a Poor Prognosis for Human Rectal Cancer of Stage II/III 
I. Chang


ST11. Detect 0.1% Low Frequency Somatic Variants in Cell-free DNA Using Oncomine™ cfDNA Assays and Ion Torrent Sequencing 
K. Bramlett

 

ST12. A Novel Fusion of TFE-3 and LINC01010 in Renal Cell Carcinoma 
O. Rouhi

 

ST13.  Spectrum of RAS Mutations in 946 Korean Patients with Metastatic Colorectal Cancer
S.H. Han

 

ST14. A Novel AKAP13-NTRK3 Fusion in a Radiation-induced Sarcoma of the Central Nervous System 
O. Rouhi


ST15.  Defining the Molecular Profile in Patients with Non-small Cell Lung Carcinoma (NSCLC) and its Relation to First-line Treatment in a Comprehensive Cancer Center in Mexico City

M. Ibarra-Meneses


ST16.  C1GALT1 Promotes EGFR Activity and is a Potential Therapeutic Target for Head and Neck Squamous Cell Carcinoma
M.C. Lin


ST17.  Correlating MDM2 and CDK4 Amplification Levels in Dedifferentiated Liposarcoma (DDLS) with Tumor Behavior and Patient Outcome
Y. Liu


ST18. MUC20 Knockdown Suppresses Malignant Phenotypes of Pancreatic Ductal Adenocarcinoma Cells Induced by Pancreatic Stellate Cells 
S.T. Chen


ST19. Detection and Classification of Clinical Tumor Variants Using the QIAGEN GeneReader NGS System 
S.Turner


ST20. Application of Liquid Biopsy to Uncover Critical Cancer Insights Using the GeneReader NGS System 
L. Andruzzi


ST21. Using GeneReader NGS System to Identify Germline and Somatic Mutations in BRCA 1/2 Genes 
O. Biglia


ST22. Frequency of EGFR Mutations among Multiethnic Filipino Patients in a Tertiary Care Setting 
C.K. Estuye


ST23. A Comprehensive DNA & RNA Pediatric Cancer Panel 
T.J. Triche

 

ST24. WITHDRAWN 

ST25. Specific and Reliable Detection of NTRK Rearrangements in IHC-positive FFPE Samples of Solid Tumours by Nanostring Technology 
S. Wagener


ST26. Methylation Analysis of APC, AXIN2, DACT1, RASSF1A and MGMT Gene Promoters in Non-small Cell Lung Cancer 
A. Saetta


ST27. Expression Analysis of Wnt Pathway in Colorectal and Breast Cancer
A. Saetta


ST28.  High-throughput Sequencing-based Routine Clinical Diagnostics on Tumor Samples: Experience with the Illumina TruSight Tumor 15 Assay
B.J. Foth


ST29. Clinical Evaluation of a Rapid Cell-free EGFR Mutation Detection Kit in Plasma from NSCLC Patients 
G. Potikyan


ST30. IDH1/2 Mutations in Gliomas: A Single Tertiary Cancer Institutional Experience 
M.Y. Gurav


ST31. IQFISH Lung Cancer Panel Probes on DAKO Omnis - A Walkaway Automation for Lung Cancer FISH 
A. Khare


ST32.  Absence of MGMT Promoter Hypermethylation in H3 K27M-mutated Diffuse Midline Gliomas WHO Grade IV
R. Banan


ST33. Detection of Somatic Alterations in Circulating Cell-free DNA of Esophageal Carcinoma Patients during Primary Staging is Predictive for Post-surgical Tumor Recurrence 
H. Pasternack


ST34. Genomic Data Illustrates Informative Roles for Gene Expression and Methylation Profiles for Tumor Classification 
K. Aldape


ST35. Comparison of Two Testing Methodologies for EGFR Mutation Screening of cfDNA from Lung Cancer Patients 
M. Sundstrom

 

ST36. A Patient-lke Circulating Tumor DNA (ctDNA) Reference Material 
M. Ryder


ST37. Experience of Cancer Genomic Profiling of Hong Kong Chinese Cohorts 
L.P. Wong

 

ST38LB. Sensitive Sequencing Method for Detection of Actionable Cancer-driver Somatic Mutations in Specimens with Scarce Material
E. Golomb

 

ST39LB.  Mutational Analysis of FOXL2 Gene Assisting in the Diagnosis of Recurrent Adult Granulosa Cell Tumor with Unusual Morphology
T. Dolkar

 

ST40LB. Identification of Biomarkers for Prostate Cancer by DNA Methylation Analysis 
T. Dillinger

 

ST41LB. Molecular Profiling of Epidermal Growth Factor Receptor in Tunisian Patients with Non Small Cell Lung Cancer Using Real Time PCR 
A. Arfaoui

 

ST42LB. External Quality Assessment for Molecular Pathology: Lessons Learned and the Need for Continued Quality Improvement 
S.J. Patton

 

ST43LB. Next Generation Sequencing of Malignant Mullerian Mixed Tumours Identifies Gene Alterations with Potential Clinical Actionability 
E. Bellini

 

ST44LB. Identification of New Molecular Pathways Involved in Endometrial Cancer Progression
E. Bellini

 

ST45LB. ALK-IHC is a Better Predictor for Outcome after ALK Inhibition with Crizotinib than ALK-FISH in Stage IV Non-small Cell Lung Cancer 
E.J. Speel

 

ST46LB. MET Overexpression, Amplification and Exon-14 Skipping in Patients with Resected NSCLC: Prevalence and Clinical Association Results from the European Thoracic Oncology Platform Lungscape Project 
E.J. Speel

 

ST47LB. Evaluation of a Promising Molecular Biomarker (CRTC1-MAML2 Rearrangement) Towards Improved Management in Mucoepidermoid Carcinoma (Head & Neck and Thoracic) – Initial Tertiary Care Hospital Experience 
A. Chaturvedi

 

ST48LB. Multi-site Reproducibility and Analytic Accuracy of the HTG EdgeSeq Immuno-oncology Assay
R. Chesser


TECHNICAL TOPICS 

TT01. Rapid and Cost-effective Custom Oncology Panels for NEBNext Direct Target Enrichment from Modular, Predesigned Genes 
C. Hendrickson


TT02. Comprehensive Detection of all Major Classes of MET Deregulation by Anchored Multiplex PCR and Next-generation Sequencing 
B.A. Kudlow


TT03. Rapid and Comprehensive Detection of CFTR Variants across Ethnic Groups Using Anchored Multiplex PCR and Next-generation Sequencing 
M.T. Hardison

 
TT04. Anchored Multiplex PCR Enables Sensitive and Specific Detection of Variants in Circulating Tumor DNA by Next-generation Sequencing 
J.E. Lee

 
TT05. Characterization of Hematologic Malignancies with Anchored Multiplex PCR and Next-generation Sequencing 
J. Haimes


TT06.  B- and T-cell Immune Repertoire Characterization by Anchored Multiplex PCR and Next-generation Sequencing
J. Eberlein


TT07. A Targeted Resequencing Approach to Identify Actionable Somatic Copy Number Alterations with High Sensitivity alongside SNVs and Indels from Clinical Tumor Specimens 
F. De La Vega


TT08. Detection of Hotspot Cancer Mutations in a Clinical Laboratory Using Next Generation Sequencing on the Ion Torrent PGM 
R. Shahsiah


TT09. Implementation of a Comprehensive NGS Workflow as an Integrated Solution for Clinical Cancer Diagnosis 
S. Lupo


TT10. A Full Process Control for setting up an NGS Operation Using the GeneReader System 
A. Darwanto


TT11. Comparison of Custom Designed Gene Panels for Hybrid Capture-based Parallel Sequencing in Molecular Pathology Routine Diagnostics 
C. Heydt


TT12. Liquid Biopsy: EGFR Mutation Testing Using Cell-free DNA and the GeneReader Workflow in a Cohort of Patients with Advanced EGFR-mutant NSCLC 
J. Seitz

 

TT13. Multi Institutional Evaluation of a High Sensitive NGS Assay for Liquid Biopsy Mutation Detection in Lung Cancer 
C. Vollbrecht


TT14. EGFR Mutation Analysis in ct-DNA from NSCLC Patients
A. Saetta

TT15. Crude Lysates from FFPE Tissues are Well Suited for Copy Number Analysis by a Novel Digital MLPA Assay 
L. Atanesyan


TT16. Molecular Analysis of Circulating Free DNA (cfDNA) from Lung Cancer Patients in Routine Laboratory Practice: A Cross-platform Comparison of Three Different Molecular Methods for Mutation Detection
S. Bartels


TT17. Analysis of SHOX2 / PTGER4 DNA Methylation for Lung Cancer Detection in Liquid Biopsies is Robust against Specific Variations in Blood Collection, Transport, and Storage Conditions 
O. Hasinger


TT18. Mass Spectrometric Imaging for the Molecular Analysis of FFPE Tumor Sections 
S.O. Deininger


TT19. Application of the GeneReader NGS System in Clinical Testing of Tumor Samples 
P. Zhang


TT20. Analysis of Clinical Relevant Mutations by the Novel Gene Reader NGS System 
U. Koitzsch


TT21. Novel rhPCR Assays for Sensitive and Accurate Detection of Germline SNPs and Somatic Mutations 
C. Chen


TT22. Development of a Breast and Lung Cancer Research Panel to Target Therapeutically Relevant Copy Number and Gene Fusion Variants from Blood 
J.J. Schageman